Folate and Prevention of neural tube defects: new insights from a bayesian model

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Autoren

  • A. Ströhle
  • T.  Bohn

Externe Organisationen

  • Institute of Science and Technology, Luxembourg
Forschungs-netzwerk anzeigen

Details

OriginalspracheEnglisch
Seiten (von - bis)109-111
Seitenumfang3
FachzeitschriftInternational Journal for Vitamin and Nutrition Research
Jahrgang85
Ausgabenummer3-4
PublikationsstatusVeröffentlicht - 2015

Abstract

Maternal folate status before and during pregnancy influences a woman's risk of having a pregnancy affected by congenital malformations of the neural tube (neural tube defects, NTD). For NTD prevention, it is recommended that women use periconceptional supplementation of folic acid. However, the recommended dose varies considerably (400 - 800 μg folic acid/day). Insufficient data exists on the relation between folate status and the risk of NTD. A recent study published in the British Medical Journal provides evidence for a generalizable dose-response relation between folate status and risk of NTD. The lowest risk of having a child with NTD was related to red blood cell (RBC) folate concentrations of ≥ 1000 nmol/L.

ASJC Scopus Sachgebiete

Ziele für nachhaltige Entwicklung

Zitieren

Folate and Prevention of neural tube defects: new insights from a bayesian model. / Ströhle, A.; Bohn, T. .
in: International Journal for Vitamin and Nutrition Research, Jahrgang 85, Nr. 3-4, 2015, S. 109-111.

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Download
@article{de5c0cd6edf34cf7970b12c10b7d0ef1,
title = "Folate and Prevention of neural tube defects: new insights from a bayesian model",
abstract = "Maternal folate status before and during pregnancy influences a woman's risk of having a pregnancy affected by congenital malformations of the neural tube (neural tube defects, NTD). For NTD prevention, it is recommended that women use periconceptional supplementation of folic acid. However, the recommended dose varies considerably (400 - 800 μg folic acid/day). Insufficient data exists on the relation between folate status and the risk of NTD. A recent study published in the British Medical Journal provides evidence for a generalizable dose-response relation between folate status and risk of NTD. The lowest risk of having a child with NTD was related to red blood cell (RBC) folate concentrations of ≥ 1000 nmol/L.",
author = "A. Str{\"o}hle and T.  Bohn",
note = "Publisher Copyright: {\textcopyright} 2015 Hans Huber Publishers, Hogrefe AG, Bern. Copyright: Copyright 2017 Elsevier B.V., All rights reserved.",
year = "2015",
doi = "10.1024/0300-9831/a000229",
language = "English",
volume = "85",
pages = "109--111",
journal = "International Journal for Vitamin and Nutrition Research",
issn = "1664-2821",
publisher = "Verlag Hans Huber",
number = "3-4",

}

Download

TY - JOUR

T1 - Folate and Prevention of neural tube defects: new insights from a bayesian model

AU - Ströhle, A.

AU - Bohn, T. 

N1 - Publisher Copyright: © 2015 Hans Huber Publishers, Hogrefe AG, Bern. Copyright: Copyright 2017 Elsevier B.V., All rights reserved.

PY - 2015

Y1 - 2015

N2 - Maternal folate status before and during pregnancy influences a woman's risk of having a pregnancy affected by congenital malformations of the neural tube (neural tube defects, NTD). For NTD prevention, it is recommended that women use periconceptional supplementation of folic acid. However, the recommended dose varies considerably (400 - 800 μg folic acid/day). Insufficient data exists on the relation between folate status and the risk of NTD. A recent study published in the British Medical Journal provides evidence for a generalizable dose-response relation between folate status and risk of NTD. The lowest risk of having a child with NTD was related to red blood cell (RBC) folate concentrations of ≥ 1000 nmol/L.

AB - Maternal folate status before and during pregnancy influences a woman's risk of having a pregnancy affected by congenital malformations of the neural tube (neural tube defects, NTD). For NTD prevention, it is recommended that women use periconceptional supplementation of folic acid. However, the recommended dose varies considerably (400 - 800 μg folic acid/day). Insufficient data exists on the relation between folate status and the risk of NTD. A recent study published in the British Medical Journal provides evidence for a generalizable dose-response relation between folate status and risk of NTD. The lowest risk of having a child with NTD was related to red blood cell (RBC) folate concentrations of ≥ 1000 nmol/L.

UR - http://www.scopus.com/inward/record.url?scp=84962182329&partnerID=8YFLogxK

U2 - 10.1024/0300-9831/a000229

DO - 10.1024/0300-9831/a000229

M3 - Article

VL - 85

SP - 109

EP - 111

JO - International Journal for Vitamin and Nutrition Research

JF - International Journal for Vitamin and Nutrition Research

SN - 1664-2821

IS - 3-4

ER -