Details
| Originalsprache | Englisch |
|---|---|
| Seiten (von - bis) | 3116-3127 |
| Seitenumfang | 12 |
| Fachzeitschrift | European Journal of Organic Chemistry |
| Jahrgang | 2005 |
| Ausgabenummer | 14 |
| Publikationsstatus | Veröffentlicht - 4 Juli 2005 |
| Extern publiziert | Ja |
Abstract
A practical route is described for the preparation of myo-inositol phosphates. Optically pure compounds can be prepared, in both forms, from p-benzoquinone by enzymatic resolution of a diacetoxyconduritol key intermediate. Monosubstituted inositol derivatives can be obtained by breaking the C2 symmetry of conduritol B derivatives. A wide variety of myo-inositol phosphates can be synthesized by combining the previously reported symmetrical approach with this new non-symmetrical approach.
ASJC Scopus Sachgebiete
- Chemie (insg.)
- Physikalische und Theoretische Chemie
- Chemie (insg.)
- Organische Chemie
Zitieren
- Standard
- Harvard
- Apa
- Vancouver
- BibTex
- RIS
in: European Journal of Organic Chemistry, Jahrgang 2005, Nr. 14, 04.07.2005, S. 3116-3127.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Flexible Stereo- and Regioselective Synthesis of myo-Inositol Phosphates (Part 2)
T2 - Via Nonsymmetrical Conduritol B Derivatives
AU - Podeschwa, Michael A.L.
AU - Plettenburg, Oliver
AU - Altenbach, Hans Josef
PY - 2005/7/4
Y1 - 2005/7/4
N2 - A practical route is described for the preparation of myo-inositol phosphates. Optically pure compounds can be prepared, in both forms, from p-benzoquinone by enzymatic resolution of a diacetoxyconduritol key intermediate. Monosubstituted inositol derivatives can be obtained by breaking the C2 symmetry of conduritol B derivatives. A wide variety of myo-inositol phosphates can be synthesized by combining the previously reported symmetrical approach with this new non-symmetrical approach.
AB - A practical route is described for the preparation of myo-inositol phosphates. Optically pure compounds can be prepared, in both forms, from p-benzoquinone by enzymatic resolution of a diacetoxyconduritol key intermediate. Monosubstituted inositol derivatives can be obtained by breaking the C2 symmetry of conduritol B derivatives. A wide variety of myo-inositol phosphates can be synthesized by combining the previously reported symmetrical approach with this new non-symmetrical approach.
KW - Asymmetric synthesis
KW - Biocatalytic resolution
KW - Inositol phosphates
KW - Natural products
KW - Phosphorylation
KW - Protecting groups
UR - http://www.scopus.com/inward/record.url?scp=22544476849&partnerID=8YFLogxK
U2 - 10.1002/ejoc.200400918
DO - 10.1002/ejoc.200400918
M3 - Article
AN - SCOPUS:22544476849
VL - 2005
SP - 3116
EP - 3127
JO - European Journal of Organic Chemistry
JF - European Journal of Organic Chemistry
SN - 1434-193X
IS - 14
ER -