Details
| Originalsprache | Englisch |
|---|---|
| Seiten (von - bis) | 5-9 |
| Seitenumfang | 5 |
| Fachzeitschrift | Iranian Journal of Otorhinolaryngology |
| Jahrgang | 29 |
| Ausgabenummer | 1 |
| Publikationsstatus | Veröffentlicht - 2017 |
Abstract
Introduction: Visualization of inner ear structures is a valuable strategy for researchers and clinicians working on hearing pathologies. Optical coherence tomography (OCT) is a high-resolution imaging technology which may be used for the visualization of tissues. In this experimental study we aimed to evaluate inner ear anatomy in well-prepared human labyrinthine bones. Materials and Methods: Three fresh human explanted temporal bones were trimmed, chemically decalcified with ethylenediaminetetraacetic acid (EDTA), and mechanically drilled under visual control using OCT in order to reveal the remaining bone shell. After confirming decalcification with a computed tomography (CT) scan, the samples were scanned with OCT in different views. The oval window, round window, and remnant part of internal auditory canal and cochlear turn were investigated. Results: Preparation of the labyrinthine bone and visualization under OCT guidance was successfully performed to a remaining bony layer of 300μm thickness. OCT images of the specimen allowed a detailed view of the intra-cochlear anatomy. Conclusion: OCT is applicable in the well-prepared human inner ear and allows visualization of soft tissue parts.
ASJC Scopus Sachgebiete
- Medizin (insg.)
- Hals-Nasen-Ohrenheilkunde
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in: Iranian Journal of Otorhinolaryngology, Jahrgang 29, Nr. 1, 2017, S. 5-9.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Experimental Visualization of Labyrinthine Structure with Optical Coherence Tomography
AU - Mohebbi, Saleh
AU - Mirsalehi, Marjan
AU - Kahrs, Lüder Alexander
AU - Ortmaier, Tobias
AU - Lenarz, Thomas
AU - Majdani, Omid
N1 - Funding information: This work has been supported by the Hearing4all excellence cluster grant and project number MA 4038/3-2 provided by DFG (German Research Foundation) and Institute of Mechatronic System (IMES) OCT II Grant Number OR 196/17-2.
PY - 2017
Y1 - 2017
N2 - Introduction: Visualization of inner ear structures is a valuable strategy for researchers and clinicians working on hearing pathologies. Optical coherence tomography (OCT) is a high-resolution imaging technology which may be used for the visualization of tissues. In this experimental study we aimed to evaluate inner ear anatomy in well-prepared human labyrinthine bones. Materials and Methods: Three fresh human explanted temporal bones were trimmed, chemically decalcified with ethylenediaminetetraacetic acid (EDTA), and mechanically drilled under visual control using OCT in order to reveal the remaining bone shell. After confirming decalcification with a computed tomography (CT) scan, the samples were scanned with OCT in different views. The oval window, round window, and remnant part of internal auditory canal and cochlear turn were investigated. Results: Preparation of the labyrinthine bone and visualization under OCT guidance was successfully performed to a remaining bony layer of 300μm thickness. OCT images of the specimen allowed a detailed view of the intra-cochlear anatomy. Conclusion: OCT is applicable in the well-prepared human inner ear and allows visualization of soft tissue parts.
AB - Introduction: Visualization of inner ear structures is a valuable strategy for researchers and clinicians working on hearing pathologies. Optical coherence tomography (OCT) is a high-resolution imaging technology which may be used for the visualization of tissues. In this experimental study we aimed to evaluate inner ear anatomy in well-prepared human labyrinthine bones. Materials and Methods: Three fresh human explanted temporal bones were trimmed, chemically decalcified with ethylenediaminetetraacetic acid (EDTA), and mechanically drilled under visual control using OCT in order to reveal the remaining bone shell. After confirming decalcification with a computed tomography (CT) scan, the samples were scanned with OCT in different views. The oval window, round window, and remnant part of internal auditory canal and cochlear turn were investigated. Results: Preparation of the labyrinthine bone and visualization under OCT guidance was successfully performed to a remaining bony layer of 300μm thickness. OCT images of the specimen allowed a detailed view of the intra-cochlear anatomy. Conclusion: OCT is applicable in the well-prepared human inner ear and allows visualization of soft tissue parts.
KW - Cochlea
KW - Decalcification
KW - Labyrinth
KW - Optical Coherence Tomography
UR - http://www.scopus.com/inward/record.url?scp=85010450452&partnerID=8YFLogxK
U2 - 10.22038/ijorl.2016.8062
DO - 10.22038/ijorl.2016.8062
M3 - Article
AN - SCOPUS:85010450452
VL - 29
SP - 5
EP - 9
JO - Iranian Journal of Otorhinolaryngology
JF - Iranian Journal of Otorhinolaryngology
SN - 2251-7251
IS - 1
ER -