Employing microtechnology for noninvasive determination of local blood oxygen saturation based on tissue remission spectra

Publikation: Beitrag in Buch/Bericht/Sammelwerk/KonferenzbandAufsatz in KonferenzbandForschungPeer-Review

Autoren

  • Gerd Ehret
  • Ignaz Thiemann
  • Eduard Reithmeier
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Details

OriginalspracheEnglisch
Titel des SammelwerksDiagnostic Optical Spectroscopy in Biomedicine II
Seiten202-213
Seitenumfang12
PublikationsstatusVeröffentlicht - 8 Okt. 2003
VeranstaltungDiagnostic Optical Spectroscopy in Biomedicine II - Munich, Deutschland
Dauer: 24 Juni 200325 Juni 2003

Publikationsreihe

NameProceedings of SPIE - The International Society for Optical Engineering
Herausgeber (Verlag)SPIE
Band5141
ISSN (Print)0277-786X

Abstract

A new micro measurement system - according to the principle of the EMPHO-System - has been developed to record tissue remission spectra within the range of 510 to 590 nm. The device hardware basically involves a white LED, optical fibers, and a miniaturized grating spectrometer. In general, exact computation of blood oxygen saturation and relative hemoglobin concentration from these tissue remisson spectra is not possible. The main reason is that - except for oxyhemoglobin and desoxyhemoglobin - many other light-scattering and light-absorbing substances such as dopa-melanin and bilirubin cause measurement errors. A new algorithm for the determination of local blood oxygen saturation and relative hemoglobin concentration from tissue remisson spectra is presented. This method is based on the probability of light photons propagation and reference coefficients. In addition, the algorithm also takes other light-scattering and light-absorbance substances in biological tissue into consideration. The method is compared with the standard procedure of Kubelka and Munk. Among others these two approaches are applied to the tissue remission spectra of ischaemia with subsequent reactive hyperemia. The calculated blood oxygen saturation and relative hemoglobin concentration of both methods are presented and discussed.

ASJC Scopus Sachgebiete

Zitieren

Employing microtechnology for noninvasive determination of local blood oxygen saturation based on tissue remission spectra. / Ehret, Gerd; Thiemann, Ignaz; Reithmeier, Eduard.
Diagnostic Optical Spectroscopy in Biomedicine II. 2003. S. 202-213 (Proceedings of SPIE - The International Society for Optical Engineering; Band 5141).

Publikation: Beitrag in Buch/Bericht/Sammelwerk/KonferenzbandAufsatz in KonferenzbandForschungPeer-Review

Ehret, G, Thiemann, I & Reithmeier, E 2003, Employing microtechnology for noninvasive determination of local blood oxygen saturation based on tissue remission spectra. in Diagnostic Optical Spectroscopy in Biomedicine II. Proceedings of SPIE - The International Society for Optical Engineering, Bd. 5141, S. 202-213, Diagnostic Optical Spectroscopy in Biomedicine II, Munich, Deutschland, 24 Juni 2003. https://doi.org/10.1117/12.500052
Ehret, G., Thiemann, I., & Reithmeier, E. (2003). Employing microtechnology for noninvasive determination of local blood oxygen saturation based on tissue remission spectra. In Diagnostic Optical Spectroscopy in Biomedicine II (S. 202-213). (Proceedings of SPIE - The International Society for Optical Engineering; Band 5141). https://doi.org/10.1117/12.500052
Ehret G, Thiemann I, Reithmeier E. Employing microtechnology for noninvasive determination of local blood oxygen saturation based on tissue remission spectra. in Diagnostic Optical Spectroscopy in Biomedicine II. 2003. S. 202-213. (Proceedings of SPIE - The International Society for Optical Engineering). doi: 10.1117/12.500052
Ehret, Gerd ; Thiemann, Ignaz ; Reithmeier, Eduard. / Employing microtechnology for noninvasive determination of local blood oxygen saturation based on tissue remission spectra. Diagnostic Optical Spectroscopy in Biomedicine II. 2003. S. 202-213 (Proceedings of SPIE - The International Society for Optical Engineering).
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abstract = "A new micro measurement system - according to the principle of the EMPHO-System - has been developed to record tissue remission spectra within the range of 510 to 590 nm. The device hardware basically involves a white LED, optical fibers, and a miniaturized grating spectrometer. In general, exact computation of blood oxygen saturation and relative hemoglobin concentration from these tissue remisson spectra is not possible. The main reason is that - except for oxyhemoglobin and desoxyhemoglobin - many other light-scattering and light-absorbing substances such as dopa-melanin and bilirubin cause measurement errors. A new algorithm for the determination of local blood oxygen saturation and relative hemoglobin concentration from tissue remisson spectra is presented. This method is based on the probability of light photons propagation and reference coefficients. In addition, the algorithm also takes other light-scattering and light-absorbance substances in biological tissue into consideration. The method is compared with the standard procedure of Kubelka and Munk. Among others these two approaches are applied to the tissue remission spectra of ischaemia with subsequent reactive hyperemia. The calculated blood oxygen saturation and relative hemoglobin concentration of both methods are presented and discussed.",
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