Details
| Originalsprache | Englisch |
|---|---|
| Seiten (von - bis) | 223-227 |
| Seitenumfang | 5 |
| Fachzeitschrift | Journal of Thrombosis and Thrombolysis |
| Jahrgang | 35 |
| Ausgabenummer | 2 |
| Publikationsstatus | Veröffentlicht - 13 Juli 2012 |
Abstract
Stroke and other thromboembolic events are mainly caused by emboli from heart, aorta and other arteries. In this paper we describe a group of 5 middle-aged patients suffering from emboli caused by large thrombi in the aorta. Since the development of giant thrombi under high flow conditions in the aorta is a pathophysiological process which is not well understood, a model of flow distribution by numerically simulating the Navier-Stokes equation for an incompressible fluid was generated. This model simulated how such thrombi may develop in the aorta. We hypothesize that large thrombi issuing from the aortic vessel wall represent a underestimated entity in middleaged persons and are probably overlooked as the cause of stroke or other embolic events in some cases.
ASJC Scopus Sachgebiete
- Medizin (insg.)
- Hämatologie
- Medizin (insg.)
- Kardiologie und kardiovaskuläre Medizin
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in: Journal of Thrombosis and Thrombolysis, Jahrgang 35, Nr. 2, 13.07.2012, S. 223-227.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Embolic events caused by aortic thrombi
T2 - An underestimated entity?
AU - Stoevesandt, Dietrich
AU - Klempt, Carsten
AU - Scheubel, Robert
AU - Herr, Waldemar
AU - Hettwer, Stefan
AU - Werdan, Karl
AU - Silber, Rolf Edgar
AU - Kraya, Torsten
AU - Thews, Oliver
AU - Schlitt, Axel
N1 - Funding information: Acknowledgments C.K. and W.H. acknowledge support from the Centre for Quantum Engineering and Space–Time Research QUEST.
PY - 2012/7/13
Y1 - 2012/7/13
N2 - Stroke and other thromboembolic events are mainly caused by emboli from heart, aorta and other arteries. In this paper we describe a group of 5 middle-aged patients suffering from emboli caused by large thrombi in the aorta. Since the development of giant thrombi under high flow conditions in the aorta is a pathophysiological process which is not well understood, a model of flow distribution by numerically simulating the Navier-Stokes equation for an incompressible fluid was generated. This model simulated how such thrombi may develop in the aorta. We hypothesize that large thrombi issuing from the aortic vessel wall represent a underestimated entity in middleaged persons and are probably overlooked as the cause of stroke or other embolic events in some cases.
AB - Stroke and other thromboembolic events are mainly caused by emboli from heart, aorta and other arteries. In this paper we describe a group of 5 middle-aged patients suffering from emboli caused by large thrombi in the aorta. Since the development of giant thrombi under high flow conditions in the aorta is a pathophysiological process which is not well understood, a model of flow distribution by numerically simulating the Navier-Stokes equation for an incompressible fluid was generated. This model simulated how such thrombi may develop in the aorta. We hypothesize that large thrombi issuing from the aortic vessel wall represent a underestimated entity in middleaged persons and are probably overlooked as the cause of stroke or other embolic events in some cases.
KW - Aorta
KW - Thromboembolic events
KW - Thrombus
UR - http://www.scopus.com/inward/record.url?scp=84877037299&partnerID=8YFLogxK
U2 - 10.1007/s11239-012-0775-x
DO - 10.1007/s11239-012-0775-x
M3 - Article
C2 - 22791080
AN - SCOPUS:84877037299
VL - 35
SP - 223
EP - 227
JO - Journal of Thrombosis and Thrombolysis
JF - Journal of Thrombosis and Thrombolysis
SN - 0929-5305
IS - 2
ER -