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Electrochemical Method for the Design of New Possible Gadolinium-Based Contrast Agents

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Autorschaft

  • Claudia Carbone
  • Aaron Stoeckle
  • Manuel Minardi
  • Fulvio Uggeri

Externe Organisationen

  • Università degli Studi di Milano-Bicocca (UNIMIB)
  • Bracco Imaging SpA
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  • Mentions
    • Blog Mentions: 1
    • News Mentions: 1
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Details

OriginalspracheEnglisch
Aufsatznummer1979
Seitenumfang12
FachzeitschriftNanomaterials
Jahrgang14
Ausgabenummer24
PublikationsstatusVeröffentlicht - 10 Dez. 2024

Abstract

Magnetic resonance imaging (MRI) is a technique that employs strong magnetic fields and radio frequencies to generate detailed images of the body’s interior. In oncology patients, gadolinium-based contrast agents (GBCAs) are frequently administered to enhance the visualization of tumors. Those contrast agents are gadolinium chelates, characterized by high stability that prevents the release of the toxic gadolinium ion into the body. This work is part of the research for alternative nanoscaled GBCAs. Following the synthesis and characterization of zinc hexacyanoferrate nanoparticles, gadolinium ions were successfully incorporated into a hexacyanoferrate-based matrix, deposited on FTO-coated glass used as working electrode in a gadolinium salt solution, by applying a fixed potential determined through cyclic voltammetry studies. The presence of gadolinium inside the matrix was confirmed by EDX.

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Zitieren

Electrochemical Method for the Design of New Possible Gadolinium-Based Contrast Agents. / Carbone, Claudia; Stoeckle, Aaron; Minardi, Manuel et al.
in: Nanomaterials, Jahrgang 14, Nr. 24, 1979, 10.12.2024.

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Carbone, C, Stoeckle, A, Minardi, M, Uggeri, F, Lattuada, L, Minguzzi, A & Vertova, A 2024, 'Electrochemical Method for the Design of New Possible Gadolinium-Based Contrast Agents', Nanomaterials, Jg. 14, Nr. 24, 1979. https://doi.org/10.3390/nano14241979
Carbone, C., Stoeckle, A., Minardi, M., Uggeri, F., Lattuada, L., Minguzzi, A., & Vertova, A. (2024). Electrochemical Method for the Design of New Possible Gadolinium-Based Contrast Agents. Nanomaterials, 14(24), Artikel 1979. https://doi.org/10.3390/nano14241979
Carbone C, Stoeckle A, Minardi M, Uggeri F, Lattuada L, Minguzzi A et al. Electrochemical Method for the Design of New Possible Gadolinium-Based Contrast Agents. Nanomaterials. 2024 Dez 10;14(24):1979. doi: 10.3390/nano14241979
Carbone, Claudia ; Stoeckle, Aaron ; Minardi, Manuel et al. / Electrochemical Method for the Design of New Possible Gadolinium-Based Contrast Agents. in: Nanomaterials. 2024 ; Jahrgang 14, Nr. 24.
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AU - Stoeckle, Aaron

AU - Minardi, Manuel

AU - Uggeri, Fulvio

AU - Lattuada, Luciano

AU - Minguzzi, Alessandro

AU - Vertova, Alberto

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