Details
Originalsprache | Englisch |
---|---|
Aufsatznummer | 1979 |
Seitenumfang | 12 |
Fachzeitschrift | Nanomaterials |
Jahrgang | 14 |
Ausgabenummer | 24 |
Publikationsstatus | Veröffentlicht - 10 Dez. 2024 |
Abstract
Magnetic resonance imaging (MRI) is a technique that employs strong magnetic fields and radio frequencies to generate detailed images of the body’s interior. In oncology patients, gadolinium-based contrast agents (GBCAs) are frequently administered to enhance the visualization of tumors. Those contrast agents are gadolinium chelates, characterized by high stability that prevents the release of the toxic gadolinium ion into the body. This work is part of the research for alternative nanoscaled GBCAs. Following the synthesis and characterization of zinc hexacyanoferrate nanoparticles, gadolinium ions were successfully incorporated into a hexacyanoferrate-based matrix, deposited on FTO-coated glass used as working electrode in a gadolinium salt solution, by applying a fixed potential determined through cyclic voltammetry studies. The presence of gadolinium inside the matrix was confirmed by EDX.
ASJC Scopus Sachgebiete
- Chemische Verfahrenstechnik (insg.)
- Allgemeine chemische Verfahrenstechnik
- Werkstoffwissenschaften (insg.)
- Allgemeine Materialwissenschaften
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in: Nanomaterials, Jahrgang 14, Nr. 24, 1979, 10.12.2024.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Electrochemical Method for the Design of New Possible Gadolinium-Based Contrast Agents
AU - Carbone, Claudia
AU - Stoeckle, Aaron
AU - Minardi, Manuel
AU - Uggeri, Fulvio
AU - Lattuada, Luciano
AU - Minguzzi, Alessandro
AU - Vertova, Alberto
N1 - Publisher Copyright: © 2024 by the authors.
PY - 2024/12/10
Y1 - 2024/12/10
N2 - Magnetic resonance imaging (MRI) is a technique that employs strong magnetic fields and radio frequencies to generate detailed images of the body’s interior. In oncology patients, gadolinium-based contrast agents (GBCAs) are frequently administered to enhance the visualization of tumors. Those contrast agents are gadolinium chelates, characterized by high stability that prevents the release of the toxic gadolinium ion into the body. This work is part of the research for alternative nanoscaled GBCAs. Following the synthesis and characterization of zinc hexacyanoferrate nanoparticles, gadolinium ions were successfully incorporated into a hexacyanoferrate-based matrix, deposited on FTO-coated glass used as working electrode in a gadolinium salt solution, by applying a fixed potential determined through cyclic voltammetry studies. The presence of gadolinium inside the matrix was confirmed by EDX.
AB - Magnetic resonance imaging (MRI) is a technique that employs strong magnetic fields and radio frequencies to generate detailed images of the body’s interior. In oncology patients, gadolinium-based contrast agents (GBCAs) are frequently administered to enhance the visualization of tumors. Those contrast agents are gadolinium chelates, characterized by high stability that prevents the release of the toxic gadolinium ion into the body. This work is part of the research for alternative nanoscaled GBCAs. Following the synthesis and characterization of zinc hexacyanoferrate nanoparticles, gadolinium ions were successfully incorporated into a hexacyanoferrate-based matrix, deposited on FTO-coated glass used as working electrode in a gadolinium salt solution, by applying a fixed potential determined through cyclic voltammetry studies. The presence of gadolinium inside the matrix was confirmed by EDX.
KW - gadolinium ion
KW - gadolinium-based contrast agents
KW - ZnHCF nanoparticles
UR - http://www.scopus.com/inward/record.url?scp=85213479895&partnerID=8YFLogxK
U2 - 10.3390/nano14241979
DO - 10.3390/nano14241979
M3 - Article
AN - SCOPUS:85213479895
VL - 14
JO - Nanomaterials
JF - Nanomaterials
SN - 2079-4991
IS - 24
M1 - 1979
ER -