TY - JOUR

T1 - Efficient synthesis of novel bis(dihydropyrano[2,3-c]pyrazoles), bis(4Hchromenes) and bis(dihydropyrano[3,2-c]chromenes) with amide functionality

AU - Abdella, Amna M.

AU - Abdelmoniem, Amr M.

AU - Butenschön, Holger

AU - Abdelhamid, Ismail A.

AU - Elwahy, Ahmed H.M.

N1 - Funding information: The authors thank the Alexander von Humboldt Foundation for postdoctoral fellowship. The authors also thank Hannover University for NMR access facilities.

PY - 2019/12/17

Y1 - 2019/12/17

N2 - A synthesis of novel bis(1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitriles), bis(4H-chromene-3-carbonitriles) and bis(dihydropyrano[3,2-c]chromenes), which are linked to aliphatic spacers via amide linkages was achieved via multicomponent reactions (MCR) of the appropriate bis-aldehyde with two equivalents of both of malononitrile and 3-methylpyrazol-5-one, dimedone or 4-hydroxycoumarin in a basic solution.

AB - A synthesis of novel bis(1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitriles), bis(4H-chromene-3-carbonitriles) and bis(dihydropyrano[3,2-c]chromenes), which are linked to aliphatic spacers via amide linkages was achieved via multicomponent reactions (MCR) of the appropriate bis-aldehyde with two equivalents of both of malononitrile and 3-methylpyrazol-5-one, dimedone or 4-hydroxycoumarin in a basic solution.

KW - 2-c]chromene)

KW - 3-c]pyrazole)

KW - Amide linkages

KW - Bis(chromene)

KW - Bis(pyrano[2

KW - Bis(pyrano[3

UR - http://www.scopus.com/inward/record.url?scp=85079062277&partnerID=8YFLogxK

U2 - 10.24820/ark.5550190.p011.071

DO - 10.24820/ark.5550190.p011.071

M3 - Article

AN - SCOPUS:85079062277

VL - 2019

SP - 306

EP - 324

JO - Arkivoc

JF - Arkivoc

SN - 1551-7004

IS - 6

ER -