Details
| Originalsprache | Englisch |
|---|---|
| Seiten (von - bis) | 129-133 |
| Seitenumfang | 5 |
| Fachzeitschrift | Journal of functional foods |
| Jahrgang | 3 |
| Ausgabenummer | 2 |
| Publikationsstatus | Veröffentlicht - Apr. 2011 |
Abstract
Fish oil capsules with gastric acid resistant coatings have been shown to lower undesirable side effects. We compared the eicosapentaenoic acid (EPA). +. docosahexaenoic acid (DHA) uptake from uncoated and coated fish oil capsules. In a double-blinded crossover trial 12 healthy young men (mean age 31. years) were randomized to 1680. mg EPA. +. DHA as triacylglycerols in uncoated or coated fish oil capsules. Fatty acid levels were analyzed in plasma phospholipids at baseline and 2, 4, 6, 8, 24, 48 and 72. h after capsule ingestion. Statistical group comparisons on the basis of area under the curve values revealed no significant differences for EPA, DHA and total n-3 fatty acid levels between the different capsule formulations. In conclusion, this nutrikinetic study indicates that coating of fish oil capsules with a gastric acid resistant layer has no influence on the bioavailability of EPA. +. DHA.
ASJC Scopus Sachgebiete
- Agrar- und Biowissenschaften (insg.)
- Lebensmittelwissenschaften
- Medizin (insg.)
- Medizin (sonstige)
- Pflege (insg.)
- Ernährung und Diätetik
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in: Journal of functional foods, Jahrgang 3, Nr. 2, 04.2011, S. 129-133.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Effect of gastric acid resistant coating of fish oil capsules on intestinal uptake of eicosapentaenoic acid and docosahexaenoic acid
AU - Schneider, Inga
AU - Schuchardt, Jan Philipp
AU - Meyer, Henrike
AU - Hahn, Andreas
PY - 2011/4
Y1 - 2011/4
N2 - Fish oil capsules with gastric acid resistant coatings have been shown to lower undesirable side effects. We compared the eicosapentaenoic acid (EPA). +. docosahexaenoic acid (DHA) uptake from uncoated and coated fish oil capsules. In a double-blinded crossover trial 12 healthy young men (mean age 31. years) were randomized to 1680. mg EPA. +. DHA as triacylglycerols in uncoated or coated fish oil capsules. Fatty acid levels were analyzed in plasma phospholipids at baseline and 2, 4, 6, 8, 24, 48 and 72. h after capsule ingestion. Statistical group comparisons on the basis of area under the curve values revealed no significant differences for EPA, DHA and total n-3 fatty acid levels between the different capsule formulations. In conclusion, this nutrikinetic study indicates that coating of fish oil capsules with a gastric acid resistant layer has no influence on the bioavailability of EPA. +. DHA.
AB - Fish oil capsules with gastric acid resistant coatings have been shown to lower undesirable side effects. We compared the eicosapentaenoic acid (EPA). +. docosahexaenoic acid (DHA) uptake from uncoated and coated fish oil capsules. In a double-blinded crossover trial 12 healthy young men (mean age 31. years) were randomized to 1680. mg EPA. +. DHA as triacylglycerols in uncoated or coated fish oil capsules. Fatty acid levels were analyzed in plasma phospholipids at baseline and 2, 4, 6, 8, 24, 48 and 72. h after capsule ingestion. Statistical group comparisons on the basis of area under the curve values revealed no significant differences for EPA, DHA and total n-3 fatty acid levels between the different capsule formulations. In conclusion, this nutrikinetic study indicates that coating of fish oil capsules with a gastric acid resistant layer has no influence on the bioavailability of EPA. +. DHA.
KW - Absorption
KW - Bioavailability
KW - DHA
KW - Enteric coating
KW - EPA
KW - Omega-3 fatty acids
UR - http://www.scopus.com/inward/record.url?scp=79954996251&partnerID=8YFLogxK
U2 - 10.1016/j.jff.2011.03.001
DO - 10.1016/j.jff.2011.03.001
M3 - Article
AN - SCOPUS:79954996251
VL - 3
SP - 129
EP - 133
JO - Journal of functional foods
JF - Journal of functional foods
SN - 1756-4646
IS - 2
ER -