Die Häufigkeit von diagnostizierten Fettlebererkrankungen (NAFLD) in der deutschen Bevölkerung – Eine Analyse auf der Basis von GKV-Routinedaten

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Autoren

  • Jona T Stahmeyer
  • Melissa Hemmerling
  • Birte Burger
  • Sveja Eberhard
  • Christian Krauth
  • Jan Zeidler
  • Annika Herr
  • Henning Weseloh
  • Siegbert Rossol

Externe Organisationen

  • AOK - Die Gesundheitskasse für Niedersachsen
  • Medizinische Hochschule Hannover (MHH)
  • Krankenhaus Nordwest GmbH
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Details

Titel in ÜbersetzungFrequency of diagnosed non-alcololic fatty liver disease (NAFLD) in the German population - An analysis based on health insurance data
OriginalspracheDeutsch
Seiten (von - bis)851-858
Seitenumfang8
FachzeitschriftZeitschrift für Gastroenterologie
Jahrgang59
Ausgabenummer8
Frühes Online-Datum23 März 2021
PublikationsstatusVeröffentlicht - 1 Aug. 2021

Abstract

BACKGROUND:  Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases in Germany. In the long term, there is an increased risk of developing liver cirrhosis and subsequent diseases. Epidemiologic studies on NAFLD prevalence in Germany are scarce. The aim of the study was to assess administrative incidence and prevalence or, more specifically, the number of patients diagnosed with NAFLD in the period from 2008 to 2018.

METHODS:  Analyses are based on administrative data of a large statutory health insurance fund. All individuals who were insured in the year of analysis and in the three-year pre-observation period were included (between 1.7-2 million insured per analysis year). NAFLD-patients were identified using relevant ICD-10 codes (K76.0 und K75.8).

RESULTS:  In 2018, 4.66 % of insured persons had a NAFLD diagnosis, 0.87 % were diagnosed first-time. Diagnoses of nonalcoholic steatohepatitis (NASH) were comparatively rare (0.09 %). Data show an uptake of NAFLD diagnoses over time. The number of incident cases per year has hardly changed. Patients with diseases of the metabolic syndrome had an increased chance of being diagnosed with NAFLD.

CONCLUSION:  It becomes evident that NAFLD is frequently diagnosed in everyday medical practice, although data from population-based studies suggest an even higher prevalence.

Schlagwörter

    epidemiology, frequency of diagnosis, incidence, NAFLD, NASH, prevalence

ASJC Scopus Sachgebiete

Zitieren

Die Häufigkeit von diagnostizierten Fettlebererkrankungen (NAFLD) in der deutschen Bevölkerung – Eine Analyse auf der Basis von GKV-Routinedaten. / Stahmeyer, Jona T; Hemmerling, Melissa; Burger, Birte et al.
in: Zeitschrift für Gastroenterologie, Jahrgang 59, Nr. 8, 01.08.2021, S. 851-858.

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Stahmeyer, JT, Hemmerling, M, Burger, B, Eberhard, S, Krauth, C, Zeidler, J, Herr, A, Weseloh, H & Rossol, S 2021, 'Die Häufigkeit von diagnostizierten Fettlebererkrankungen (NAFLD) in der deutschen Bevölkerung – Eine Analyse auf der Basis von GKV-Routinedaten', Zeitschrift für Gastroenterologie, Jg. 59, Nr. 8, S. 851-858. https://doi.org/10.1055/a-1402-1263
Stahmeyer, J. T., Hemmerling, M., Burger, B., Eberhard, S., Krauth, C., Zeidler, J., Herr, A., Weseloh, H., & Rossol, S. (2021). Die Häufigkeit von diagnostizierten Fettlebererkrankungen (NAFLD) in der deutschen Bevölkerung – Eine Analyse auf der Basis von GKV-Routinedaten. Zeitschrift für Gastroenterologie, 59(8), 851-858. https://doi.org/10.1055/a-1402-1263
Stahmeyer JT, Hemmerling M, Burger B, Eberhard S, Krauth C, Zeidler J et al. Die Häufigkeit von diagnostizierten Fettlebererkrankungen (NAFLD) in der deutschen Bevölkerung – Eine Analyse auf der Basis von GKV-Routinedaten. Zeitschrift für Gastroenterologie. 2021 Aug 1;59(8):851-858. Epub 2021 Mär 23. doi: 10.1055/a-1402-1263
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T1 - Die Häufigkeit von diagnostizierten Fettlebererkrankungen (NAFLD) in der deutschen Bevölkerung – Eine Analyse auf der Basis von GKV-Routinedaten

AU - Stahmeyer, Jona T

AU - Hemmerling, Melissa

AU - Burger, Birte

AU - Eberhard, Sveja

AU - Krauth, Christian

AU - Zeidler, Jan

AU - Herr, Annika

AU - Weseloh, Henning

AU - Rossol, Siegbert

PY - 2021/8/1

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N2 - BACKGROUND:  Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases in Germany. In the long term, there is an increased risk of developing liver cirrhosis and subsequent diseases. Epidemiologic studies on NAFLD prevalence in Germany are scarce. The aim of the study was to assess administrative incidence and prevalence or, more specifically, the number of patients diagnosed with NAFLD in the period from 2008 to 2018.METHODS:  Analyses are based on administrative data of a large statutory health insurance fund. All individuals who were insured in the year of analysis and in the three-year pre-observation period were included (between 1.7-2 million insured per analysis year). NAFLD-patients were identified using relevant ICD-10 codes (K76.0 und K75.8).RESULTS:  In 2018, 4.66 % of insured persons had a NAFLD diagnosis, 0.87 % were diagnosed first-time. Diagnoses of nonalcoholic steatohepatitis (NASH) were comparatively rare (0.09 %). Data show an uptake of NAFLD diagnoses over time. The number of incident cases per year has hardly changed. Patients with diseases of the metabolic syndrome had an increased chance of being diagnosed with NAFLD.CONCLUSION:  It becomes evident that NAFLD is frequently diagnosed in everyday medical practice, although data from population-based studies suggest an even higher prevalence.

AB - BACKGROUND:  Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases in Germany. In the long term, there is an increased risk of developing liver cirrhosis and subsequent diseases. Epidemiologic studies on NAFLD prevalence in Germany are scarce. The aim of the study was to assess administrative incidence and prevalence or, more specifically, the number of patients diagnosed with NAFLD in the period from 2008 to 2018.METHODS:  Analyses are based on administrative data of a large statutory health insurance fund. All individuals who were insured in the year of analysis and in the three-year pre-observation period were included (between 1.7-2 million insured per analysis year). NAFLD-patients were identified using relevant ICD-10 codes (K76.0 und K75.8).RESULTS:  In 2018, 4.66 % of insured persons had a NAFLD diagnosis, 0.87 % were diagnosed first-time. Diagnoses of nonalcoholic steatohepatitis (NASH) were comparatively rare (0.09 %). Data show an uptake of NAFLD diagnoses over time. The number of incident cases per year has hardly changed. Patients with diseases of the metabolic syndrome had an increased chance of being diagnosed with NAFLD.CONCLUSION:  It becomes evident that NAFLD is frequently diagnosed in everyday medical practice, although data from population-based studies suggest an even higher prevalence.

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