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Development of a combined OCT-Raman probe for the prospective in vivo clinical melanoma skin cancer screening

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

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OriginalspracheEnglisch
Aufsatznummer105103
FachzeitschriftReview of Scientific Instruments
Jahrgang88
Ausgabenummer10
PublikationsstatusVeröffentlicht - 4 Okt. 2017

Abstract

A combined optical coherence tomography (OCT)-Raman probe was designed and built into a spectral domain OCT head, and its performance was evaluated and compared to the most common Raman probe setups, based on a fiber bundle and confocal free space optics. Due to the use of the full field of view of an OCT scanning lens, the combined probe has a superior performance within maximum permissible exposure limits, compared to the other two probes. Skin Raman spectra, recorded in vivo, further prove the feasibility of the OCT-Raman probe for the future in vivo clinical applications in skin cancer screening.

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Development of a combined OCT-Raman probe for the prospective in vivo clinical melanoma skin cancer screening. / Mazurenka, Mikhail ; Behrendt, Lea; Wollweber, Merve et al.
in: Review of Scientific Instruments, Jahrgang 88, Nr. 10, 105103, 04.10.2017.

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Mazurenka, Mikhail ; Behrendt, Lea ; Wollweber, Merve et al. / Development of a combined OCT-Raman probe for the prospective in vivo clinical melanoma skin cancer screening. in: Review of Scientific Instruments. 2017 ; Jahrgang 88, Nr. 10.
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abstract = "A combined optical coherence tomography (OCT)-Raman probe was designed and built into a spectral domain OCT head, and its performance was evaluated and compared to the most common Raman probe setups, based on a fiber bundle and confocal free space optics. Due to the use of the full field of view of an OCT scanning lens, the combined probe has a superior performance within maximum permissible exposure limits, compared to the other two probes. Skin Raman spectra, recorded in vivo, further prove the feasibility of the OCT-Raman probe for the future in vivo clinical applications in skin cancer screening.",
author = "Mikhail Mazurenka and Lea Behrendt and Merve Wollweber and Uwe Morgner and Roth, {Bernhard Wilhelm}",
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AU - Mazurenka, Mikhail

AU - Behrendt, Lea

AU - Wollweber, Merve

AU - Morgner, Uwe

AU - Roth, Bernhard Wilhelm

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