Details
Originalsprache | Englisch |
---|---|
Aufsatznummer | 105103 |
Fachzeitschrift | Review of Scientific Instruments |
Jahrgang | 88 |
Ausgabenummer | 10 |
Publikationsstatus | Veröffentlicht - 4 Okt. 2017 |
Abstract
A combined optical coherence tomography (OCT)-Raman probe was designed and built into a spectral domain OCT head, and its performance was evaluated and compared to the most common Raman probe setups, based on a fiber bundle and confocal free space optics. Due to the use of the full field of view of an OCT scanning lens, the combined probe has a superior performance within maximum permissible exposure limits, compared to the other two probes. Skin Raman spectra, recorded in vivo, further prove the feasibility of the OCT-Raman probe for the future in vivo clinical applications in skin cancer screening.
ASJC Scopus Sachgebiete
- Physik und Astronomie (insg.)
- Instrumentierung
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in: Review of Scientific Instruments, Jahrgang 88, Nr. 10, 105103, 04.10.2017.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Development of a combined OCT-Raman probe for the prospective in vivo clinical melanoma skin cancer screening
AU - Mazurenka, Mikhail
AU - Behrendt, Lea
AU - Wollweber, Merve
AU - Morgner, Uwe
AU - Roth, Bernhard Wilhelm
N1 - Funding information: This work was supported by the German Federal Ministry of Education and Research (BMBF) within the VIP-project MeDiOO (Grant No. 03V0826).
PY - 2017/10/4
Y1 - 2017/10/4
N2 - A combined optical coherence tomography (OCT)-Raman probe was designed and built into a spectral domain OCT head, and its performance was evaluated and compared to the most common Raman probe setups, based on a fiber bundle and confocal free space optics. Due to the use of the full field of view of an OCT scanning lens, the combined probe has a superior performance within maximum permissible exposure limits, compared to the other two probes. Skin Raman spectra, recorded in vivo, further prove the feasibility of the OCT-Raman probe for the future in vivo clinical applications in skin cancer screening.
AB - A combined optical coherence tomography (OCT)-Raman probe was designed and built into a spectral domain OCT head, and its performance was evaluated and compared to the most common Raman probe setups, based on a fiber bundle and confocal free space optics. Due to the use of the full field of view of an OCT scanning lens, the combined probe has a superior performance within maximum permissible exposure limits, compared to the other two probes. Skin Raman spectra, recorded in vivo, further prove the feasibility of the OCT-Raman probe for the future in vivo clinical applications in skin cancer screening.
UR - http://www.scopus.com/inward/record.url?scp=85031767318&partnerID=8YFLogxK
U2 - 10.1063/1.5004999
DO - 10.1063/1.5004999
M3 - Article
C2 - 29092508
AN - SCOPUS:85031767318
VL - 88
JO - Review of Scientific Instruments
JF - Review of Scientific Instruments
SN - 0034-6748
IS - 10
M1 - 105103
ER -