Details
| Originalsprache | Englisch |
|---|---|
| Seiten (von - bis) | 5273-5275 |
| Seitenumfang | 3 |
| Fachzeitschrift | Tetrahedron Letters |
| Jahrgang | 49 |
| Ausgabenummer | 36 |
| Publikationsstatus | Veröffentlicht - 28 Juni 2008 |
Abstract
In this work synthetic and semi-synthetic studies toward the antitumor active natural product tonantzitlolone B are described, starting with an advanced intermediate obtained from the total synthesis of tonantzitlolone and a natural sample of this compound, respectively. The unknown absolute configuration of the stereogenic center in the side chain was elucidated to be (R).
ASJC Scopus Sachgebiete
- Biochemie, Genetik und Molekularbiologie (insg.)
- Biochemie
- Pharmakologie, Toxikologie und Pharmazie (insg.)
- Wirkstoffforschung
- Chemie (insg.)
- Organische Chemie
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in: Tetrahedron Letters, Jahrgang 49, Nr. 36, 28.06.2008, S. 5273-5275.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Determination of the absolute configuration of the diterpene tonantzitlolone B
AU - Busch, Torsten
AU - Schuster, Hannah
AU - Kirschning, Andreas
N1 - Funding information: The work was funded by a graduate scholarship for T.B. provided by the Stiftung Stipendien-Fonds des Verbandes der Chemischen Industrie. We thank AnalytiCon Discovery GmbH (Potsdam, Germany) for providing a sample of authentic Tonantzitlolone B.
PY - 2008/6/28
Y1 - 2008/6/28
N2 - In this work synthetic and semi-synthetic studies toward the antitumor active natural product tonantzitlolone B are described, starting with an advanced intermediate obtained from the total synthesis of tonantzitlolone and a natural sample of this compound, respectively. The unknown absolute configuration of the stereogenic center in the side chain was elucidated to be (R).
AB - In this work synthetic and semi-synthetic studies toward the antitumor active natural product tonantzitlolone B are described, starting with an advanced intermediate obtained from the total synthesis of tonantzitlolone and a natural sample of this compound, respectively. The unknown absolute configuration of the stereogenic center in the side chain was elucidated to be (R).
KW - Diterpenes
KW - Natural products
KW - Semisynthesis
KW - Structure elucidation
KW - Total synthesis
UR - http://www.scopus.com/inward/record.url?scp=47549104916&partnerID=8YFLogxK
U2 - 10.1016/j.tetlet.2008.06.105
DO - 10.1016/j.tetlet.2008.06.105
M3 - Article
AN - SCOPUS:47549104916
VL - 49
SP - 5273
EP - 5275
JO - Tetrahedron Letters
JF - Tetrahedron Letters
SN - 0040-4039
IS - 36
ER -