Degradation of MgF2-coated and uncoated MgNd2 specimens in contact with nasal mucosa

Publikation: Beitrag in Buch/Bericht/Sammelwerk/KonferenzbandAufsatz in KonferenzbandForschungPeer-Review

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  • Medizinische Hochschule Hannover (MHH)
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OriginalspracheEnglisch
Titel des SammelwerksMagnesium Technology 2016 - Held During TMS 2016
Untertitel145th Annual Meeting and Exhibition
Herausgeber/-innenAlok Singh, Kiran Solanki, Michele Viola Manuel, Neale R. Neelameggham
Herausgeber (Verlag)Minerals, Metals and Materials Society
Seiten331-335
Seitenumfang5
ISBN (elektronisch)9781119225805
PublikationsstatusVeröffentlicht - 4 Feb. 2016
VeranstaltungMagnesium Technology 2016 - TMS 2016: 145th Annual Meeting and Exhibition - Nashville, USA / Vereinigte Staaten
Dauer: 14 Feb. 201618 Feb. 2016

Publikationsreihe

NameMagnesium Technology
Band2016-January
ISSN (Print)1545-4150

Abstract

The magnesium-neodymium alloy MgNd2 offers an elongation of 30%. Therefore, it is well suited as a material for resorbable stents which can be used for treating chronic sinusitis. While the alloy's corrosion properties were already investigated in vitro, the present study focuses on the in vivo degradation behavior of fluoride-coated and uncoated specimens in direct contact with porcine nasal mucosa during a period of 180 days. The study showed a promising and controlled biodegradation, which was investigated by measurements of the MgNd2 specimens' mass and volume losses as well as element analyses on the surface to obtain information about the composition of the degradation layer. The degradation rates of the uncoated samples in direct contact with the physiological tissue showed a maximum during the first 45 days which then decreased for the remaining implantation period. In contrast, the degradation rates of the fluoride-coated samples increased gradually during the implantation duration.

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Degradation of MgF2-coated and uncoated MgNd2 specimens in contact with nasal mucosa. / Eifler, Rainer; Durisin, Martin; Klose, Christian et al.
Magnesium Technology 2016 - Held During TMS 2016: 145th Annual Meeting and Exhibition. Hrsg. / Alok Singh; Kiran Solanki; Michele Viola Manuel; Neale R. Neelameggham. Minerals, Metals and Materials Society, 2016. S. 331-335 (Magnesium Technology; Band 2016-January).

Publikation: Beitrag in Buch/Bericht/Sammelwerk/KonferenzbandAufsatz in KonferenzbandForschungPeer-Review

Eifler, R, Durisin, M, Klose, C, Lenarz, T & Maier, HJ 2016, Degradation of MgF2-coated and uncoated MgNd2 specimens in contact with nasal mucosa. in A Singh, K Solanki, MV Manuel & NR Neelameggham (Hrsg.), Magnesium Technology 2016 - Held During TMS 2016: 145th Annual Meeting and Exhibition. Magnesium Technology, Bd. 2016-January, Minerals, Metals and Materials Society, S. 331-335, Magnesium Technology 2016 - TMS 2016: 145th Annual Meeting and Exhibition, Nashville, USA / Vereinigte Staaten, 14 Feb. 2016. https://doi.org/10.1002/9781119274803.ch64
Eifler, R., Durisin, M., Klose, C., Lenarz, T., & Maier, H. J. (2016). Degradation of MgF2-coated and uncoated MgNd2 specimens in contact with nasal mucosa. In A. Singh, K. Solanki, M. V. Manuel, & N. R. Neelameggham (Hrsg.), Magnesium Technology 2016 - Held During TMS 2016: 145th Annual Meeting and Exhibition (S. 331-335). (Magnesium Technology; Band 2016-January). Minerals, Metals and Materials Society. https://doi.org/10.1002/9781119274803.ch64
Eifler R, Durisin M, Klose C, Lenarz T, Maier HJ. Degradation of MgF2-coated and uncoated MgNd2 specimens in contact with nasal mucosa. in Singh A, Solanki K, Manuel MV, Neelameggham NR, Hrsg., Magnesium Technology 2016 - Held During TMS 2016: 145th Annual Meeting and Exhibition. Minerals, Metals and Materials Society. 2016. S. 331-335. (Magnesium Technology). doi: 10.1002/9781119274803.ch64
Eifler, Rainer ; Durisin, Martin ; Klose, Christian et al. / Degradation of MgF2-coated and uncoated MgNd2 specimens in contact with nasal mucosa. Magnesium Technology 2016 - Held During TMS 2016: 145th Annual Meeting and Exhibition. Hrsg. / Alok Singh ; Kiran Solanki ; Michele Viola Manuel ; Neale R. Neelameggham. Minerals, Metals and Materials Society, 2016. S. 331-335 (Magnesium Technology).
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title = "Degradation of MgF2-coated and uncoated MgNd2 specimens in contact with nasal mucosa",
abstract = "The magnesium-neodymium alloy MgNd2 offers an elongation of 30%. Therefore, it is well suited as a material for resorbable stents which can be used for treating chronic sinusitis. While the alloy's corrosion properties were already investigated in vitro, the present study focuses on the in vivo degradation behavior of fluoride-coated and uncoated specimens in direct contact with porcine nasal mucosa during a period of 180 days. The study showed a promising and controlled biodegradation, which was investigated by measurements of the MgNd2 specimens' mass and volume losses as well as element analyses on the surface to obtain information about the composition of the degradation layer. The degradation rates of the uncoated samples in direct contact with the physiological tissue showed a maximum during the first 45 days which then decreased for the remaining implantation period. In contrast, the degradation rates of the fluoride-coated samples increased gradually during the implantation duration.",
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Download

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T1 - Degradation of MgF2-coated and uncoated MgNd2 specimens in contact with nasal mucosa

AU - Eifler, Rainer

AU - Durisin, Martin

AU - Klose, Christian

AU - Lenarz, Thomas

AU - Maier, Hans Jürgen

N1 - Publisher Copyright: Copyright © 2016 by The Minerals, Metals & Materials Society. All rights reserved. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.

PY - 2016/2/4

Y1 - 2016/2/4

N2 - The magnesium-neodymium alloy MgNd2 offers an elongation of 30%. Therefore, it is well suited as a material for resorbable stents which can be used for treating chronic sinusitis. While the alloy's corrosion properties were already investigated in vitro, the present study focuses on the in vivo degradation behavior of fluoride-coated and uncoated specimens in direct contact with porcine nasal mucosa during a period of 180 days. The study showed a promising and controlled biodegradation, which was investigated by measurements of the MgNd2 specimens' mass and volume losses as well as element analyses on the surface to obtain information about the composition of the degradation layer. The degradation rates of the uncoated samples in direct contact with the physiological tissue showed a maximum during the first 45 days which then decreased for the remaining implantation period. In contrast, the degradation rates of the fluoride-coated samples increased gradually during the implantation duration.

AB - The magnesium-neodymium alloy MgNd2 offers an elongation of 30%. Therefore, it is well suited as a material for resorbable stents which can be used for treating chronic sinusitis. While the alloy's corrosion properties were already investigated in vitro, the present study focuses on the in vivo degradation behavior of fluoride-coated and uncoated specimens in direct contact with porcine nasal mucosa during a period of 180 days. The study showed a promising and controlled biodegradation, which was investigated by measurements of the MgNd2 specimens' mass and volume losses as well as element analyses on the surface to obtain information about the composition of the degradation layer. The degradation rates of the uncoated samples in direct contact with the physiological tissue showed a maximum during the first 45 days which then decreased for the remaining implantation period. In contrast, the degradation rates of the fluoride-coated samples increased gradually during the implantation duration.

KW - Coating

KW - Corrosion

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BT - Magnesium Technology 2016 - Held During TMS 2016

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Y2 - 14 February 2016 through 18 February 2016

ER -

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