Comparison between Modelflow® and echocardiography in the determination of cardiac output during and following pregnancy at rest and during exercise

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Autoren

  • Victoria L. Meah
  • Karianne Backx
  • Rob E. Shave
  • Eric J. Stöhr
  • Stephen Mark Cooper

Externe Organisationen

  • Cardiff Metropolitan University
  • University of British Columbia
  • Columbia University Irving Medical Center
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Details

OriginalspracheEnglisch
Seiten (von - bis)1-20
Seitenumfang20
FachzeitschriftJournal of Human Sport and Exercise
Jahrgang17
Ausgabenummer1
PublikationsstatusVeröffentlicht - 2020
Extern publiziertJa

Abstract

During pregnancy, assessment of cardiac output (Q), a fundamental measure of cardiovascular function, provides important insight into maternal adaptation. However, methods for dynamic Q measurement require validation. The purpose of this study was to estimate the agreement of Q measured by echocardiography and Modelflow® at rest and during submaximal exercise in non-pregnant (n = 18), pregnant (n = 15, 22-26 weeks gestation) and postpartum women (n = 12, 12-16 weeks post-delivery). Simultaneous measurements of ˙ derived from echocardiography [criterion] and Modelflow® were obtained at rest and during low-moderate intensity (25% and 50% peak power output) cycling exercise and compared using Bland-Altman analysis and limits of agreement. Agreement between echocardiography and Modelflow® was poor in non-pregnant, pregnant and postpartum women at rest (mean difference ± SD:-1.1 ± 3.4;-1.2 ± 2.9;-1.9 ± 3.2 L. min-1), and this remained evident during exercise. The Modelflow® method is not recommended for Q determination in research involving young, healthy non-pregnant and pregnant women at rest or during dynamic challenge. Previously published Q data from studies utilising this method should be interpreted with caution.

ASJC Scopus Sachgebiete

Zitieren

Comparison between Modelflow® and echocardiography in the determination of cardiac output during and following pregnancy at rest and during exercise. / Meah, Victoria L.; Backx, Karianne; Shave, Rob E. et al.
in: Journal of Human Sport and Exercise, Jahrgang 17, Nr. 1, 2020, S. 1-20.

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Meah VL, Backx K, Shave RE, Stöhr EJ, Cooper SM. Comparison between Modelflow® and echocardiography in the determination of cardiac output during and following pregnancy at rest and during exercise. Journal of Human Sport and Exercise. 2020;17(1):1-20. doi: 10.14198/JHSE.2022.171.12
Meah, Victoria L. ; Backx, Karianne ; Shave, Rob E. et al. / Comparison between Modelflow® and echocardiography in the determination of cardiac output during and following pregnancy at rest and during exercise. in: Journal of Human Sport and Exercise. 2020 ; Jahrgang 17, Nr. 1. S. 1-20.
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abstract = "During pregnancy, assessment of cardiac output (Q), a fundamental measure of cardiovascular function, provides important insight into maternal adaptation. However, methods for dynamic Q measurement require validation. The purpose of this study was to estimate the agreement of Q measured by echocardiography and Modelflow{\textregistered} at rest and during submaximal exercise in non-pregnant (n = 18), pregnant (n = 15, 22-26 weeks gestation) and postpartum women (n = 12, 12-16 weeks post-delivery). Simultaneous measurements of ˙ derived from echocardiography [criterion] and Modelflow{\textregistered} were obtained at rest and during low-moderate intensity (25% and 50% peak power output) cycling exercise and compared using Bland-Altman analysis and limits of agreement. Agreement between echocardiography and Modelflow{\textregistered} was poor in non-pregnant, pregnant and postpartum women at rest (mean difference ± SD:-1.1 ± 3.4;-1.2 ± 2.9;-1.9 ± 3.2 L. min-1), and this remained evident during exercise. The Modelflow{\textregistered} method is not recommended for Q determination in research involving young, healthy non-pregnant and pregnant women at rest or during dynamic challenge. Previously published Q data from studies utilising this method should be interpreted with caution.",
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AU - Shave, Rob E.

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N1 - Funding information: The experiments in this study comply with the current laws of the country in which they were performed. VLM's current affiliation is Program for Pregnancy and Postpartum Health, Faculty of Kinesiology, Sport, and Recreation, University of Alberta, Edmonton, Alberta, Canada. VLM is the recipient of a postdoctoral fellowship award, funded by generous supporters of the Lois Hole Hospital for Women through the Women and Children's Health Research Institute, Edmonton, Alberta, Canada.

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