Details
| Originalsprache | Englisch |
|---|---|
| Seiten (von - bis) | 9616-9619 |
| Seitenumfang | 4 |
| Fachzeitschrift | SOFT MATTER |
| Jahrgang | 7 |
| Ausgabenummer | 20 |
| Publikationsstatus | Veröffentlicht - 21 Okt. 2011 |
| Extern publiziert | Ja |
Abstract
Controlling a coil-to-helix transition in peptide-polymer conjugates with soft stimuli requires the careful balancing of stabilizing and destabilizing effects in the peptide segment. The transition between two secondary structures of a bioconjugate is realized using calcium ions to establish a biomimetic control mechanism. Regulation of Ca 2+-ion levels via competitive Ca 2+-ion binders made the process reversible.
ASJC Scopus Sachgebiete
- Chemie (insg.)
- Allgemeine Chemie
- Physik und Astronomie (insg.)
- Physik der kondensierten Materie
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in: SOFT MATTER, Jahrgang 7, Nr. 20, 21.10.2011, S. 9616-9619.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Calcium ions as bioinspired triggers to reversibly control the coil-to-helix transition in peptide-polymer conjugates
AU - Kühnle, Romina I.
AU - Gebauer, Denis
AU - Börner, Hans G.
PY - 2011/10/21
Y1 - 2011/10/21
N2 - Controlling a coil-to-helix transition in peptide-polymer conjugates with soft stimuli requires the careful balancing of stabilizing and destabilizing effects in the peptide segment. The transition between two secondary structures of a bioconjugate is realized using calcium ions to establish a biomimetic control mechanism. Regulation of Ca 2+-ion levels via competitive Ca 2+-ion binders made the process reversible.
AB - Controlling a coil-to-helix transition in peptide-polymer conjugates with soft stimuli requires the careful balancing of stabilizing and destabilizing effects in the peptide segment. The transition between two secondary structures of a bioconjugate is realized using calcium ions to establish a biomimetic control mechanism. Regulation of Ca 2+-ion levels via competitive Ca 2+-ion binders made the process reversible.
UR - http://www.scopus.com/inward/record.url?scp=80053594421&partnerID=8YFLogxK
U2 - 10.1039/c1sm05625e
DO - 10.1039/c1sm05625e
M3 - Article
AN - SCOPUS:80053594421
VL - 7
SP - 9616
EP - 9619
JO - SOFT MATTER
JF - SOFT MATTER
SN - 1744-683X
IS - 20
ER -