Details
| Originalsprache | Englisch |
|---|---|
| Titel des Sammelwerks | 3D Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine |
| Herausgeber (Verlag) | Elsevier Inc. |
| Seiten | 281-306 |
| Seitenumfang | 26 |
| ISBN (elektronisch) | 9780128006641 |
| ISBN (Print) | 9780128005477 |
| Publikationsstatus | Veröffentlicht - 6 Feb. 2015 |
| Extern publiziert | Ja |
Abstract
There is a strong demand for tissue-engineered (TE), fully functional skin for different applications. For extensive burns, and large and deep wounds, the method of autologous split-thickness skin graft, typically used in the clinic, is limited by the number and size of donor sites, and the aesthetical and/or functional outcome is often poor. Furthermore, the European cosmetics industry needs skin equivalents for product testing, since animal research for cosmetics testing is now considered illegal. TE human skin equivalents might even be a better model for the reaction of human skin. To date, there is still no skin equivalent that satisfactorily mimics natural skins' functions (or appearance), such as the capability to control body temperature with sweat glands, sensory skills, immune competence, or hair follicles. Bioprinting might enable skin generation with all necessary cells in their specific microenvironment and the corresponding functions. The first demonstrations of printed skin tissue are presented here.
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3D Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine. Elsevier Inc., 2015. S. 281-306.
Publikation: Beitrag in Buch/Bericht/Sammelwerk/Konferenzband › Beitrag in Buch/Sammelwerk › Forschung › Peer-Review
}
TY - CHAP
T1 - Bioprinting for Skin
AU - Koch, Lothar
AU - Michael, Stefanie
AU - Reimers, Kerstin
AU - Vogt, Peter M.
AU - Chichkov, Boris
N1 - Funding information: The studies described here have been supported by Deutsche Forschungsgemeinschaft, SFB TransRegio 37, REBIRTH Cluster of Excellence (Exc62/1), and by Land Niedersachsen and Volkswagenstiftung in the Biofabrication for NIFE project.
PY - 2015/2/6
Y1 - 2015/2/6
N2 - There is a strong demand for tissue-engineered (TE), fully functional skin for different applications. For extensive burns, and large and deep wounds, the method of autologous split-thickness skin graft, typically used in the clinic, is limited by the number and size of donor sites, and the aesthetical and/or functional outcome is often poor. Furthermore, the European cosmetics industry needs skin equivalents for product testing, since animal research for cosmetics testing is now considered illegal. TE human skin equivalents might even be a better model for the reaction of human skin. To date, there is still no skin equivalent that satisfactorily mimics natural skins' functions (or appearance), such as the capability to control body temperature with sweat glands, sensory skills, immune competence, or hair follicles. Bioprinting might enable skin generation with all necessary cells in their specific microenvironment and the corresponding functions. The first demonstrations of printed skin tissue are presented here.
AB - There is a strong demand for tissue-engineered (TE), fully functional skin for different applications. For extensive burns, and large and deep wounds, the method of autologous split-thickness skin graft, typically used in the clinic, is limited by the number and size of donor sites, and the aesthetical and/or functional outcome is often poor. Furthermore, the European cosmetics industry needs skin equivalents for product testing, since animal research for cosmetics testing is now considered illegal. TE human skin equivalents might even be a better model for the reaction of human skin. To date, there is still no skin equivalent that satisfactorily mimics natural skins' functions (or appearance), such as the capability to control body temperature with sweat glands, sensory skills, immune competence, or hair follicles. Bioprinting might enable skin generation with all necessary cells in their specific microenvironment and the corresponding functions. The first demonstrations of printed skin tissue are presented here.
KW - Bioprinting
KW - Laser-assisted bioprinting
KW - Laser-induced forward transfer
KW - Skin
KW - Skin printing
KW - Skin tissue generation
UR - http://www.scopus.com/inward/record.url?scp=84944411398&partnerID=8YFLogxK
U2 - 10.1016/b978-0-12-800547-7.00013-8
DO - 10.1016/b978-0-12-800547-7.00013-8
M3 - Contribution to book/anthology
AN - SCOPUS:84944411398
SN - 9780128005477
SP - 281
EP - 306
BT - 3D Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine
PB - Elsevier Inc.
ER -