Bio-field-effect Transistors for Process Control in Biotechnology

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Autoren

  • U. Brand
  • B. Reinhardt
  • F. Rüther
  • T. Scheper
  • K. Schügerl

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Details

OriginalspracheEnglisch
Seiten (von - bis)315-318
Seitenumfang4
FachzeitschriftSensors and Actuators: B. Chemical
Jahrgang4
Ausgabenummer3-4
PublikationsstatusVeröffentlicht - Juni 1991

Abstract

The application of enzyme-modified field-effect transistors (BioFETs) in biotechnological process control is presented. Penicillin, glucose and urea are detected with these devices in cultivation media and on-line in biotechnological processes. In these applications, the BioFETs are used as detectors in flow injection analysis (FIA) systems. Special flow cells with a small volume, constructed for this purpose, guarantee an optimum sample transport to the sensor. Therefore, 15-20 determinations per hour can be performed. The BioFET/FIA system gives good results for the on-line monitoring of glucose and urea during cultivations of S. cerevisiae and E. coli in different types of bioreactors.

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Bio-field-effect Transistors for Process Control in Biotechnology. / Brand, U.; Reinhardt, B.; Rüther, F. et al.
in: Sensors and Actuators: B. Chemical, Jahrgang 4, Nr. 3-4, 06.1991, S. 315-318.

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Brand U, Reinhardt B, Rüther F, Scheper T, Schügerl K. Bio-field-effect Transistors for Process Control in Biotechnology. Sensors and Actuators: B. Chemical. 1991 Jun;4(3-4):315-318. doi: 10.1016/0925-4005(91)80129-8
Brand, U. ; Reinhardt, B. ; Rüther, F. et al. / Bio-field-effect Transistors for Process Control in Biotechnology. in: Sensors and Actuators: B. Chemical. 1991 ; Jahrgang 4, Nr. 3-4. S. 315-318.
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