TY - JOUR

T1 - Antifeedant and ovicidal activities of a new cassane and other compounds from Caesalpinia welwitschiana Oliv. and Caesalpinia bonducL. against Tuta absoluta (Lepidoptera: Gelechiidae)

AU - Essoung, Flaure Rosette Ehawa

AU - Mba'ning, Brice Mitterant

AU - Tcho, Alain Tadjong

AU - Chhabra, Sumesh Chander

AU - Mohamed, Samira Abuelgasim

AU - Lenta, Bruno Ndjakou

AU - Ngouela, Silvere Augustin

AU - Tsamo, Etienne

AU - Hassanali, Ahmed

AU - Cox, Russell John

N1 - Funding Information: We gratefully acknowledge the financial support of the German Academic Exchange Service In-Region scholarship for funding FREE. SAM thanks the Federal Ministry of Cooperation and Development (BMZ), Germany for providing the financial support through ICIPE Tuta absoluta IPM project (N?: 12.1433.7-001.00). RJC acknowledges the DFG for funding for LCMS instrumentation (INST 187/621-1).

PY - 2021

Y1 - 2021

N2 - Methanolic extracts of liana of Caesalpinia welwitschiana and leaves of C. bonduc were found to possess moderate antifeedant and ovicidal activities against Tuta absoluta. Bioassay-guided isolation of constituents from the most active fraction of C. welwitschiana led to the identification of four known compounds [isobonducellin 1a and bonducellin 1 b, intricatinol 2, (-)-epigallocatechin-3-O-gallate 4] and one new constituent [welwitschianic acid 3]. The most active fraction of C. bonduc afforded two known constituents neocaesalpin L 5 and neocaesalpin A 6. The isolated structures were elucidated on the basis of their MS, UV, IR and 1 & 2 D NMR spectra and by comparison with literature data. Compounds 2, 4-6 were showed antifeedant and ovicidal properties against T. absoluta, some comparable to that of azadirachtin at 50, 100 and 200 ng/µl. Overall, the present study, conclude that the two species of the plant could be a promising source of eco-friendly botanical constituents.

AB - Methanolic extracts of liana of Caesalpinia welwitschiana and leaves of C. bonduc were found to possess moderate antifeedant and ovicidal activities against Tuta absoluta. Bioassay-guided isolation of constituents from the most active fraction of C. welwitschiana led to the identification of four known compounds [isobonducellin 1a and bonducellin 1 b, intricatinol 2, (-)-epigallocatechin-3-O-gallate 4] and one new constituent [welwitschianic acid 3]. The most active fraction of C. bonduc afforded two known constituents neocaesalpin L 5 and neocaesalpin A 6. The isolated structures were elucidated on the basis of their MS, UV, IR and 1 & 2 D NMR spectra and by comparison with literature data. Compounds 2, 4-6 were showed antifeedant and ovicidal properties against T. absoluta, some comparable to that of azadirachtin at 50, 100 and 200 ng/µl. Overall, the present study, conclude that the two species of the plant could be a promising source of eco-friendly botanical constituents.

KW - Cassanes

KW - flavonoides

KW - Tuta absoluta

KW - Antifeedant

KW - Oviposition

KW - Caesalpinia bonduc

KW - Caesalpinia welwitschiana

UR - http://www.scopus.com/inward/record.url?scp=85091605801&partnerID=8YFLogxK

U2 - 10.1080/14786419.2020.1825424

DO - 10.1080/14786419.2020.1825424

M3 - Article

VL - 35

SP - 5681

EP - 5691

JO - Natural product research

JF - Natural product research

SN - 1478-6419

IS - 24

ER -