Details
| Originalsprache | Englisch |
|---|---|
| Seiten (von - bis) | 637-639 |
| Seitenumfang | 3 |
| Fachzeitschrift | Tetrahedron Letters |
| Jahrgang | 44 |
| Ausgabenummer | 4 |
| Publikationsstatus | Veröffentlicht - 20 Jan. 2003 |
Abstract
New thiophilic polymer-bound haloate(I) complexes are presented which are well suited for the polymer-assisted solution-phase activation of 2-deoxythioglycosides. In the presence of alcohols 2-deoxyglycosides are obtained in yields between 60 and 95%. Isolation of the target glycosides is further simplified by removing the byproduct diphenyldisulfide by reductive work-up. Here also a polymer-bound reagent, namely borohydride exchange resin, served as a tool for sequestering the sulfur-containing impurities.
ASJC Scopus Sachgebiete
- Biochemie, Genetik und Molekularbiologie (insg.)
- Biochemie
- Pharmakologie, Toxikologie und Pharmazie (insg.)
- Wirkstoffforschung
- Chemie (insg.)
- Organische Chemie
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in: Tetrahedron Letters, Jahrgang 44, Nr. 4, 20.01.2003, S. 637-639.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Anomeric activation of thioglycosides and preparation of deoxyglycosides using polymer-bound iodate(I) complexes
AU - Jaunzems, Janis
AU - Sourkouni-Argirusi, Georgia
AU - Jesberger, Martin
AU - Kirschning, Andreas
PY - 2003/1/20
Y1 - 2003/1/20
N2 - New thiophilic polymer-bound haloate(I) complexes are presented which are well suited for the polymer-assisted solution-phase activation of 2-deoxythioglycosides. In the presence of alcohols 2-deoxyglycosides are obtained in yields between 60 and 95%. Isolation of the target glycosides is further simplified by removing the byproduct diphenyldisulfide by reductive work-up. Here also a polymer-bound reagent, namely borohydride exchange resin, served as a tool for sequestering the sulfur-containing impurities.
AB - New thiophilic polymer-bound haloate(I) complexes are presented which are well suited for the polymer-assisted solution-phase activation of 2-deoxythioglycosides. In the presence of alcohols 2-deoxyglycosides are obtained in yields between 60 and 95%. Isolation of the target glycosides is further simplified by removing the byproduct diphenyldisulfide by reductive work-up. Here also a polymer-bound reagent, namely borohydride exchange resin, served as a tool for sequestering the sulfur-containing impurities.
UR - http://www.scopus.com/inward/record.url?scp=0037454995&partnerID=8YFLogxK
U2 - 10.1016/S0040-4039(02)02708-9
DO - 10.1016/S0040-4039(02)02708-9
M3 - Article
AN - SCOPUS:0037454995
VL - 44
SP - 637
EP - 639
JO - Tetrahedron Letters
JF - Tetrahedron Letters
SN - 0040-4039
IS - 4
ER -