Analyzing randomized dose finding studies with a primary and a secondary endpoint

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Autoren

  • Ludwig A. Hothorn
  • Gernot Wassmer

Organisationseinheiten

Externe Organisationen

  • Universität zu Köln
Forschungs-netzwerk anzeigen

Details

OriginalspracheEnglisch
Seiten (von - bis)301-305
Seitenumfang5
FachzeitschriftJournal of Biopharmaceutical Statistics
Jahrgang13
Ausgabenummer2
PublikationsstatusVeröffentlicht - 4 Jan. 2003

Abstract

The identification of the minimum effective dose for both the primary and secondary endpoint under a priori importance ordering assumption is described. Stepwise testing procedures, which conditionally test each elementary hypotheses at level α, but control the experimentwise Type I error rate, can be used.

ASJC Scopus Sachgebiete

Zitieren

Analyzing randomized dose finding studies with a primary and a secondary endpoint. / Hothorn, Ludwig A.; Wassmer, Gernot.
in: Journal of Biopharmaceutical Statistics, Jahrgang 13, Nr. 2, 04.01.2003, S. 301-305.

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Hothorn, Ludwig A. ; Wassmer, Gernot. / Analyzing randomized dose finding studies with a primary and a secondary endpoint. in: Journal of Biopharmaceutical Statistics. 2003 ; Jahrgang 13, Nr. 2. S. 301-305.
Download
@article{2f92de2e23474516ba4a910030a395be,
title = "Analyzing randomized dose finding studies with a primary and a secondary endpoint",
abstract = "The identification of the minimum effective dose for both the primary and secondary endpoint under a priori importance ordering assumption is described. Stepwise testing procedures, which conditionally test each elementary hypotheses at level α, but control the experimentwise Type I error rate, can be used.",
keywords = "Dose finding trial, Intersection-union test, Multiple endpoints",
author = "Hothorn, {Ludwig A.} and Gernot Wassmer",
year = "2003",
month = jan,
day = "4",
doi = "10.1081/BIP-120019273",
language = "English",
volume = "13",
pages = "301--305",
journal = "Journal of Biopharmaceutical Statistics",
issn = "1054-3406",
publisher = "Taylor and Francis Ltd.",
number = "2",

}

Download

TY - JOUR

T1 - Analyzing randomized dose finding studies with a primary and a secondary endpoint

AU - Hothorn, Ludwig A.

AU - Wassmer, Gernot

PY - 2003/1/4

Y1 - 2003/1/4

N2 - The identification of the minimum effective dose for both the primary and secondary endpoint under a priori importance ordering assumption is described. Stepwise testing procedures, which conditionally test each elementary hypotheses at level α, but control the experimentwise Type I error rate, can be used.

AB - The identification of the minimum effective dose for both the primary and secondary endpoint under a priori importance ordering assumption is described. Stepwise testing procedures, which conditionally test each elementary hypotheses at level α, but control the experimentwise Type I error rate, can be used.

KW - Dose finding trial

KW - Intersection-union test

KW - Multiple endpoints

UR - http://www.scopus.com/inward/record.url?scp=0037273486&partnerID=8YFLogxK

U2 - 10.1081/BIP-120019273

DO - 10.1081/BIP-120019273

M3 - Article

C2 - 12729396

AN - SCOPUS:0037273486

VL - 13

SP - 301

EP - 305

JO - Journal of Biopharmaceutical Statistics

JF - Journal of Biopharmaceutical Statistics

SN - 1054-3406

IS - 2

ER -