Details
| Originalsprache | Englisch |
|---|---|
| Seiten (von - bis) | 5093-5095 |
| Seitenumfang | 3 |
| Fachzeitschrift | Tetrahedron letters |
| Jahrgang | 43 |
| Ausgabenummer | 29 |
| Publikationsstatus | Veröffentlicht - 15 Juli 2002 |
Abstract
The synthesis of a stereo pentade of the macrolide antibiotic oleandolide is reported. The C1-C7 fragment resembles the analogous segment of Panek's total synthesis of oleandolide. The use of the vinylogous Mukaiyama aldol reaction shortens the route significantly and has the advantage of utilizing an easily accessible ketene acetal.
ASJC Scopus Sachgebiete
- Biochemie, Genetik und Molekularbiologie (insg.)
- Biochemie
- Pharmakologie, Toxikologie und Pharmazie (insg.)
- Wirkstoffforschung
- Chemie (insg.)
- Organische Chemie
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in: Tetrahedron letters, Jahrgang 43, Nr. 29, 15.07.2002, S. 5093-5095.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Advances in the vinylogous Mukaiyama aldol reaction and its application to the synthesis of the C1-C7 subunit of oleandolide
AU - Hassfeld, Jorma
AU - Kalesse, Markus
PY - 2002/7/15
Y1 - 2002/7/15
N2 - The synthesis of a stereo pentade of the macrolide antibiotic oleandolide is reported. The C1-C7 fragment resembles the analogous segment of Panek's total synthesis of oleandolide. The use of the vinylogous Mukaiyama aldol reaction shortens the route significantly and has the advantage of utilizing an easily accessible ketene acetal.
AB - The synthesis of a stereo pentade of the macrolide antibiotic oleandolide is reported. The C1-C7 fragment resembles the analogous segment of Panek's total synthesis of oleandolide. The use of the vinylogous Mukaiyama aldol reaction shortens the route significantly and has the advantage of utilizing an easily accessible ketene acetal.
UR - http://www.scopus.com/inward/record.url?scp=0037100031&partnerID=8YFLogxK
U2 - 10.1016/S0040-4039(02)00993-0
DO - 10.1016/S0040-4039(02)00993-0
M3 - Article
AN - SCOPUS:0037100031
VL - 43
SP - 5093
EP - 5095
JO - Tetrahedron letters
JF - Tetrahedron letters
SN - 0040-4039
IS - 29
ER -