Details
| Originalsprache | Englisch |
|---|---|
| Seiten (von - bis) | 809-820 |
| Seitenumfang | 12 |
| Fachzeitschrift | Synthesis |
| Jahrgang | 50 |
| Ausgabenummer | 04 |
| Publikationsstatus | Veröffentlicht - 18 Jan. 2018 |
| Extern publiziert | Ja |
Abstract
Benzilic acid rearrangement of i -steroid ketones and their subsequent opening gives access to 5(6→7) abeo -steroids. The functional group tolerance is demonstrated by several examples, including substrates with additional olefinic groups. The method opens a potential route to the synthesis of complex natural products such as solanioic acid from abundant steroid starting materials like ergosterol.
ASJC Scopus Sachgebiete
- Chemische Verfahrenstechnik (insg.)
- Katalyse
- Chemie (insg.)
- Organische Chemie
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in: Synthesis, Jahrgang 50, Nr. 04, 18.01.2018, S. 809-820.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Access to 5(6 -> 7)abeo-Steroids through Benzilic Acid Rearrangement of i-Steroids
AU - Noack, Florian
AU - Hartmayer, Bence
AU - Heretsch, Philipp
N1 - © Georg Thieme Verlag Stuttgart · New York
PY - 2018/1/18
Y1 - 2018/1/18
N2 - Benzilic acid rearrangement of i -steroid ketones and their subsequent opening gives access to 5(6→7) abeo -steroids. The functional group tolerance is demonstrated by several examples, including substrates with additional olefinic groups. The method opens a potential route to the synthesis of complex natural products such as solanioic acid from abundant steroid starting materials like ergosterol.
AB - Benzilic acid rearrangement of i -steroid ketones and their subsequent opening gives access to 5(6→7) abeo -steroids. The functional group tolerance is demonstrated by several examples, including substrates with additional olefinic groups. The method opens a potential route to the synthesis of complex natural products such as solanioic acid from abundant steroid starting materials like ergosterol.
KW - abeo-steroids
KW - benzilic acid rearrangement
KW - i-steroids
KW - natural products
KW - total synthesis
KW - abeo -steroids
KW - i -steroids
UR - http://www.scopus.com/inward/record.url?scp=85040797786&partnerID=8YFLogxK
U2 - 10.1055/s-0036-1591883
DO - 10.1055/s-0036-1591883
M3 - Article
VL - 50
SP - 809
EP - 820
JO - Synthesis
JF - Synthesis
SN - 0039-7881
IS - 04
ER -