Details
| Originalsprache | Englisch |
|---|---|
| Titel des Sammelwerks | Biomedical Technology |
| Herausgeber/-innen | Thomas Lenarz, Peter Wriggers |
| Seiten | 41-53 |
| Seitenumfang | 13 |
| ISBN (elektronisch) | 978-3-319-10981-7 |
| Publikationsstatus | Veröffentlicht - 2015 |
Publikationsreihe
| Name | Lecture Notes in Applied and Computational Mechanics |
|---|---|
| Herausgeber (Verlag) | Springer Verlag |
| Band | 74 |
| ISSN (Print) | 1613-7736 |
Abstract
In this work a biochemical fracture healing model coupled with mechanical stimulation of stem cell differentiation is investigated. A finite element scheme is applied to the underlaying advection-diffusion-reaction problem, using the Time Discontinuous Galerkin and Finite Calculus method to ensure stability of the calculation. Strains within the callus region are computed and used for a characterization of the local mechanical demand and the resulting stimulation of the healing process. A theoretical axisymmetric model of a sheep osteotomy is implemented and results of the presented FEM approach are discussed. The repair progresswill be determined by the interfragmentary movement (IFM) and the mean tissue densities.
ASJC Scopus Sachgebiete
- Ingenieurwesen (insg.)
- Maschinenbau
- Informatik (insg.)
- Theoretische Informatik und Mathematik
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Biomedical Technology. Hrsg. / Thomas Lenarz; Peter Wriggers. 2015. S. 41-53 (Lecture Notes in Applied and Computational Mechanics; Band 74).
Publikation: Beitrag in Buch/Bericht/Sammelwerk/Konferenzband › Beitrag in Buch/Sammelwerk › Forschung › Peer-Review
}
TY - CHAP
T1 - A mechanically stimulated fracture healing model using a finite element framework
AU - Sapotnick, Alexander
AU - Nackenhorst, Udo
N1 - Funding Information: This research was founded by the German Research Foundation (Deutsche Forschungsgemeinschaft Na330/8-1).
PY - 2015
Y1 - 2015
N2 - In this work a biochemical fracture healing model coupled with mechanical stimulation of stem cell differentiation is investigated. A finite element scheme is applied to the underlaying advection-diffusion-reaction problem, using the Time Discontinuous Galerkin and Finite Calculus method to ensure stability of the calculation. Strains within the callus region are computed and used for a characterization of the local mechanical demand and the resulting stimulation of the healing process. A theoretical axisymmetric model of a sheep osteotomy is implemented and results of the presented FEM approach are discussed. The repair progresswill be determined by the interfragmentary movement (IFM) and the mean tissue densities.
AB - In this work a biochemical fracture healing model coupled with mechanical stimulation of stem cell differentiation is investigated. A finite element scheme is applied to the underlaying advection-diffusion-reaction problem, using the Time Discontinuous Galerkin and Finite Calculus method to ensure stability of the calculation. Strains within the callus region are computed and used for a characterization of the local mechanical demand and the resulting stimulation of the healing process. A theoretical axisymmetric model of a sheep osteotomy is implemented and results of the presented FEM approach are discussed. The repair progresswill be determined by the interfragmentary movement (IFM) and the mean tissue densities.
KW - Biomechanics
KW - Bone repair
KW - Finite element
KW - Fracture healing
UR - http://www.scopus.com/inward/record.url?scp=84921651649&partnerID=8YFLogxK
U2 - 10.1007/978-3-319-10981-7_3
DO - 10.1007/978-3-319-10981-7_3
M3 - Contribution to book/anthology
AN - SCOPUS:84921651649
SN - 978-3-319-10980-0
SN - 978-3-319-36020-1
T3 - Lecture Notes in Applied and Computational Mechanics
SP - 41
EP - 53
BT - Biomedical Technology
A2 - Lenarz, Thomas
A2 - Wriggers, Peter
ER -