TY - JOUR

T1 - A gated atmospheric pressure drift tube ion mobility spectrometer-time-of-flight mass spectrometer

AU - Heptner, Andre

AU - Reinecke, Tobias

AU - Langejuergen, Jens

AU - Zimmermann, Stefan

N1 - Funding information: This research is funded by the German Research Foundation ( DFG ZI 1288/1-1 ).

PY - 2014/8/22

Y1 - 2014/8/22

N2 - Identifying the compounds of an unknown gas mixture by using an ion mobility spectrometer (IMS) is a difficult task, because several ion species can be generated in the ionization process. One method to analyze the occurring peaks in an IMS spectrum is coupling an IMS to a mass spectrometer (MS). In our setup we coupled a 3H drift tube IMS to a Bruker micrOTOF II. Therefore, the detector plate of the IMS is pierced and a transfer capillary is inserted. The ions are transferred via gas flow and electric fields into the MS. The transmission of the ions through the transfer capillary can be shuttered very precisely by increasing the electric potential of the detector generating a repulsive electric field. Thus, it is possible to transfer single ion clouds of generated IMS spectra into the mass spectrometer where a corresponding mass spectrum is generated. In this work we analyze the positive and negative IMS spectra of single analytes as well as gas mixtures and characterize the occurring ion species.

AB - Identifying the compounds of an unknown gas mixture by using an ion mobility spectrometer (IMS) is a difficult task, because several ion species can be generated in the ionization process. One method to analyze the occurring peaks in an IMS spectrum is coupling an IMS to a mass spectrometer (MS). In our setup we coupled a 3H drift tube IMS to a Bruker micrOTOF II. Therefore, the detector plate of the IMS is pierced and a transfer capillary is inserted. The ions are transferred via gas flow and electric fields into the MS. The transmission of the ions through the transfer capillary can be shuttered very precisely by increasing the electric potential of the detector generating a repulsive electric field. Thus, it is possible to transfer single ion clouds of generated IMS spectra into the mass spectrometer where a corresponding mass spectrum is generated. In this work we analyze the positive and negative IMS spectra of single analytes as well as gas mixtures and characterize the occurring ion species.

KW - BTX

KW - IMS-MS-coupling

KW - Ion mobility spectrometry

KW - Peak identification

UR - http://www.scopus.com/inward/record.url?scp=84904726749&partnerID=8YFLogxK

U2 - 10.1016/j.chroma.2014.06.059

DO - 10.1016/j.chroma.2014.06.059

M3 - Article

C2 - 25015244

AN - SCOPUS:84904726749

VL - 1356

SP - 241

EP - 248

JO - Journal of Chromatography A

JF - Journal of Chromatography A

SN - 0021-9673

ER -