Details
Originalsprache | Englisch |
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Titel des Sammelwerks | Medical Imaging 2008 |
Untertitel | Image Processing |
Publikationsstatus | Veröffentlicht - 11 März 2008 |
Veranstaltung | Medical Imaging 2008: Image Processing - San Diego, CA, USA / Vereinigte Staaten Dauer: 17 Feb. 2008 → 19 Feb. 2008 |
Publikationsreihe
Name | Progress in Biomedical Optics and Imaging - Proceedings of SPIE |
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Band | 6914 |
ISSN (Print) | 1605-7422 |
Abstract
Respiratory motion is a complicating factor in radiation therapy, tumor ablation, and other treatments of the thorax and upper abdomen. In most cases, the treatment requires a demanding knowledge of the location of the organ under investigation. One approach to reduce the uncertainty of organ motion caused by breathing is to use prior knowledge of the breathing motion. In this work, we extract lung motion fields of seven patients in 4DCT inhale-exhale images using an iterative shape-constrained deformable model approach. Since data was acquired for radiotherapy planning, images of the same patient over different weeks of treatment were available. Although, respiratory motion shows a repetitive character, it is well-known that patient's variability in breathing pattern impedes motion estimation. A detailed motion field analysis is performed in order to investigate the reproducibility of breathing motion over the weeks of treatment. For that purpose, parameters being significant for breathing motion are derived. The analysis of the extracted motion fields provides a basis for a further breathing motion prediction. Patient-specific motion models are derived by averaging the extracted motion fields of each individual patient. The obtained motion models are adapted to each patient in a leave-one-out test in order to simulate motion estimation to unseen data. By using patient-specific mean motion models 60% of the breathing motion can be captured on average.
ASJC Scopus Sachgebiete
- Werkstoffwissenschaften (insg.)
- Elektronische, optische und magnetische Materialien
- Physik und Astronomie (insg.)
- Atom- und Molekularphysik sowie Optik
- Werkstoffwissenschaften (insg.)
- Biomaterialien
- Medizin (insg.)
- Radiologie, Nuklearmedizin und Bildgebung
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- BibTex
- RIS
Medical Imaging 2008: Image Processing. 2008. 69141L (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Band 6914).
Publikation: Beitrag in Buch/Bericht/Sammelwerk/Konferenzband › Aufsatz in Konferenzband › Forschung › Peer-Review
}
TY - GEN
T1 - 4DCT Image-Based Lung Motion Field Extraction and Analysis
AU - Klinder, Tobias
AU - Lorenz, Cristian
AU - Von Berg, Jens
AU - Renisch, Steffen
AU - Blaffert, Thomas
AU - Ostermann, Jörn
PY - 2008/3/11
Y1 - 2008/3/11
N2 - Respiratory motion is a complicating factor in radiation therapy, tumor ablation, and other treatments of the thorax and upper abdomen. In most cases, the treatment requires a demanding knowledge of the location of the organ under investigation. One approach to reduce the uncertainty of organ motion caused by breathing is to use prior knowledge of the breathing motion. In this work, we extract lung motion fields of seven patients in 4DCT inhale-exhale images using an iterative shape-constrained deformable model approach. Since data was acquired for radiotherapy planning, images of the same patient over different weeks of treatment were available. Although, respiratory motion shows a repetitive character, it is well-known that patient's variability in breathing pattern impedes motion estimation. A detailed motion field analysis is performed in order to investigate the reproducibility of breathing motion over the weeks of treatment. For that purpose, parameters being significant for breathing motion are derived. The analysis of the extracted motion fields provides a basis for a further breathing motion prediction. Patient-specific motion models are derived by averaging the extracted motion fields of each individual patient. The obtained motion models are adapted to each patient in a leave-one-out test in order to simulate motion estimation to unseen data. By using patient-specific mean motion models 60% of the breathing motion can be captured on average.
AB - Respiratory motion is a complicating factor in radiation therapy, tumor ablation, and other treatments of the thorax and upper abdomen. In most cases, the treatment requires a demanding knowledge of the location of the organ under investigation. One approach to reduce the uncertainty of organ motion caused by breathing is to use prior knowledge of the breathing motion. In this work, we extract lung motion fields of seven patients in 4DCT inhale-exhale images using an iterative shape-constrained deformable model approach. Since data was acquired for radiotherapy planning, images of the same patient over different weeks of treatment were available. Although, respiratory motion shows a repetitive character, it is well-known that patient's variability in breathing pattern impedes motion estimation. A detailed motion field analysis is performed in order to investigate the reproducibility of breathing motion over the weeks of treatment. For that purpose, parameters being significant for breathing motion are derived. The analysis of the extracted motion fields provides a basis for a further breathing motion prediction. Patient-specific motion models are derived by averaging the extracted motion fields of each individual patient. The obtained motion models are adapted to each patient in a leave-one-out test in order to simulate motion estimation to unseen data. By using patient-specific mean motion models 60% of the breathing motion can be captured on average.
KW - 4DCT
KW - Motion estimation
KW - Motion modeling
KW - Respiratory motion
UR - http://www.scopus.com/inward/record.url?scp=43449089228&partnerID=8YFLogxK
U2 - 10.1117/12.769407
DO - 10.1117/12.769407
M3 - Conference contribution
AN - SCOPUS:43449089228
SN - 9780819470980
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Medical Imaging 2008
T2 - Medical Imaging 2008: Image Processing
Y2 - 17 February 2008 through 19 February 2008
ER -